[发明专利]一种心脑血管疾病遗传风险评估检测panel及其应用

权利要求书

1.一种心脑血管疾病遗传风险评估检测panel，其特征在于，所述检测panel包括心脑血管疾病相关易感基因的132个SNP位点的多重PCR扩增引物对和单碱基延伸引物；

所述132个SNP位点包括rs2824292、rs361508、rs6538595、rs10744777、rs2824293、rs11067763、rs6841581、rs12122341、rs579459、rs2271037、rs11661542、rs2107595、rs1746048、rs6711736、rs9315204、rs7193343、rs1122608、rs6596140、rs9298506、rs1986743、rs3798220、rs1937506、rs2303656、rs4471613、rs264、rs2021783、rs1132274、rs879324、rs11591147、rs7961152、rs5742904、rs2304556、rs12190287、rs2820037、rs3764261、rs12204590、rs9319428、rs11110912、rs4420638、rs2505083、rs599839、rs6729869、rs429358、rs12232780、rs17465637、rs3755351、rs10889353、rs2076185、rs1412444、rs10021303、rs12654264、rs12524865、rs4977574、rs10495809、rs1883025、rs9268402、rs12413409、rs9810888、rs2954029、rs4380028、rs9369640、rs6997709、rs7412、rs11066280、rs10757274、rs3749585、rs2984613、rs7136259、rs6842241、rs820430、rs16936752、rs7865618、rs1333040、rs9308945、rs3111754、rs10069690、rs6475606、rs11196288、rs1324694、rs1333042、rs1429412、rs556621、rs877087、rs3828329、rs4628172、rs6843082、rs6449093、rs9349379、rs763497、rs17696736、rs11833579、rs12526453、rs10958409、rs2230500、rs12679196、rs2123536、rs2891168、rs12932445、rs7853368、rs10953541、rs10757278、rs11984041、rs3211928、rs11879293、rs390446、rs2723334、rs10986769、rs11066301、rs10757272、rs2200733、rs713536、rs439401、rs1042714、rs1260326、rs12425791、rs7016880、rs1805126、rs964184、rs4867131、rs17145738、rs3766871、rs326、rs3814843、rs780094、rs11720524、rs1260333、rs2283222、rs157580、rs35594137、rs12286037、rs790896、rs174546；

所述多重PCR扩增引物对的序列为SEQ ID NO.1-SEQ ID NO.264所示的核苷酸序列；

所述单碱基延伸引物的序列为SEQ ID NO.265-SEQ ID NO.396所示的核苷酸序列。