[发明专利]包含胆碱及其衍生物的组合物,其制备方法和用途在审
申请号: | 201580078684.X | 申请日: | 2015-04-21 |
公开(公告)号: | CN107529805A | 公开(公告)日: | 2018-01-02 |
发明(设计)人: | A·韦德伯格;R·努马;G·本-德罗尔;F·巴尔-约瑟夫;I·沙法特 | 申请(专利权)人: | 酶学技术有限公司 |
主分类号: | A23L33/00 | 分类号: | A23L33/00;A23L33/10;A61K31/14;A61K31/661;A23G3/36 |
代理公司: | 上海弼兴律师事务所31283 | 代理人: | 薛琦 |
地址: | 以色列卡*** | 国省代码: | 暂无信息 |
权利要求书: | 查看更多 | 说明书: | 查看更多 |
摘要: | |||
搜索关键词: | 包含 胆碱 及其 衍生物 组合 制备 方法 用途 | ||
技术领域
本发明提供了包含胆碱及其水溶性衍生物的组合物,其制备方法和用途。
背景技术
被认为与当前公开的主题背景相关的参考文献如下:
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2.Zeisel SH.Choline:an essential nutrient for humans.Nutrition 2000;16(7-8):669-671.
3.Food and Nutrition Board,Institute of Medicine.Choline.In:Dietary Reference Intakes for Thiamin,Riboflavin,Niacin,Vitamin B6,Vitamin B12,Pantothenic Acid,Biotin,and Choline.Washington,D.C.:National Academy Press,1998:390-422.
4.Holmes-McNary MQ,Cheng WL,Mar MH,Fussell S,Zeisel SH.Choline and choline esters in human and rat milk and in infant formulas.Am J Clin Nutr.1996Oct;64(4):572-6.
5.Holmes HC,Snodgrass GJ,Iles RA.Changes in the choline content of human breast milk in the first 3weeks after birth.Eur J Pediatr.2000 Mar;159(3):198-204.
6.Ilcol YO,Ozbek R,Hamurtekin E,Ulus IH.Choline status in newborns,infants,children,breast-feeding women,breast-fed infants and human breast milk.J Nutr Biochem.2005Aug;16(8):489-99.
7.Kristine Y.Patterson,Seema A.Bhagwat,Juhi R.Williams,Juliette C.Howe,and Joanne M.Holden.USDA Database for the Choline Content of Common Foods.Release Two.Nutrient Data Laboratory Agricultural Research Service U.S.Department of Agriculture.January 2008.
8.Florián J.and Warshel.Phosphate Ester Hydrolysis in Aqueous Solution:Associative versus Dissociative Mechanisms.A.J.Phys.Chem.B,1998,102(4),pp 719–734.
9.Kamerlin SC,Florián J,Warshel A.Associative versus dissociative mechanisms of phosphate monoester hydrolysis:on the interpretation of activation entropies.Chemphyschem.2008 Aug 25;9(12):1767-73.
10.Vincent JB,Crowder MW,Averill BA.Hydrolysis of phosphate monoesters:a biological problem with multiple chemical solutions.Trends Biochem Sci.1992 Mar;17(3):105-10.
11.US 2864848 A1–Method of producing 1-alpha-glycerylphosphorylcholine.
12.WO 2007/010892 A1–Novel phospholipid processing agent.
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